DR.R.V.PATHY AYURVEDA

🌡️  Why Fever Worsens Weaker Organs ✍ By Dr. Subha Rajan, BAMS 🔬 MODERN PATHOGENESIS – SYSTEMIC TO LOCAL EFFECTS ✅ Stage 1: Invasion of Pyrogens When the body detects pathogens (bacteria, virus, fungi), they release exogenous pyrogens (like LPS – lipopolysaccharide). These activate immune cells (macrophages, monocytes), which then release endogenous pyrogens: 👉 IL-1, IL-6, TNF-alpha, interferons ✅ Stage 2: Hypothalamic Thermoregulation These pyrogens reach the hypothalamus, which resets the body’s thermostat via prostaglandin E2 (PGE2). Result: Fever (Pyrexia) – elevated body temperature to support immune defense. ✅ Stage 3: Systemic Effects Begin Increased temperature causes: ↑ Heart rate ↑ Metabolism Muscle protein breakdown ↓ Appetite (energy conservation) ↑ Cortisol secretion (stress hormone) ✅Stage 4: Targeting the Weak Spots The immune system is now hyperactive, and inflammatory mediators like cytokines travel through the bloodstream. They accumulate more in areas with: Pr...

 India has been battling with a significant rise in COVID-19 cases in the second wave. A severe and rare fungal illness, Mucormycosis also known as “black fungus”, affecting somecoronavirus patients is causing a double blow to the country.  Mucormycosis infections aremore severe in people with comorbid conditions like Diabetes, Hypertension etc. and immune-compromised state.  Because of the increase in the number of patients with this deadly infection ,many states have declared Mucormycosis as an epidemic and has become a matter of hugeconcern.  Mucormycosis is classified mainly into five types depending on the part of the bodyaffected.  The clinical features described of Rhino-orbito-cerebral Mucor mycosis are similarto Raktaja Pratishyaya and Krimija Shiroroga (unilateral facial swelling, Headaches, Nasalcongestion, Nasal discharge, Fever etc).  Presentation of Pulmonary Mucormycosis are verymuch similar to Kshayaja Kasa, (Cough with pericardial chest pai...